Blastocyst Transfers

Two major contributory factors for poor take home baby rate

  • Reduced viability of replaced embryos
  • Asynchrony of stage of replaced embryo and uterine environment (stimulated endometrium)

Blastocyst culture is for improved take home baby rate. But blastocyst culture may reduce the number of embryo transfers as all embryos may not grow to the blastocyst stage & may be arrested at 4 or 6 cell stage, thus resulting in cancellation of the entire cycle.

Blastocyst culture

  • Requires sequential media
  • Day 5 or 6 transfer
  • Blastulation rate 68 – 70 %
  • Implantation rate increased – From 19 to 33 %
  • Pregnancy rare increased – From 37 to 58 %
  • Delivery rate per transfer – 52 % compared to 25% of day 2 or 3 transfer
  • With optimal cryopreservation high cumulative take home baby rate with replacement of single blastocyst (zona intact or zona free)

Blastocyst transfer gives opportunity to select better embryos with temporal synchronization of embryo and endometrium at ER

Pregnancy & live birth rate per ovum pick up similar in 2 groups but higher per embryo transfer for blastocyst transfers.

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Dr. Patil’s Fertility and Endoscopy Clinic

Center for Assisted Reproductive Technology, Endoscopic Surgery and Andrology

No 1, Uma Admirality, First Floor, Bannerghatta Road, Bangalore - 560029
Ph: 080 - 41201357, 41462419 Mobile: 9945221622

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